First Total Synthesis of Varioxiranol A

First Total Synthesis of Varioxiranol A

The paper describes the first total synthesis of natural varioxiranol A by chiral pool approach and confirmation of its absolute configuration by single-crystal X-ray analysis. The target varioxiranol A and its 4-epimer were obtained after 10 steps from single and available chiral source 1,2-O-isopr...

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Bibliographic Details
Main Authors: Angelika Lásiková, Jana Doháňošová, Mária Štiblariková, Martin Parák, Ján Moncol, Tibor Gracza
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
synthesis of natural products
varioxiranol A
4-epi-varioxiranol A
absolute structure
Emericella variecolor
Online Access:http://www.mdpi.com/1420-3049/24/5/862

Internet

http://www.mdpi.com/1420-3049/24/5/862

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