Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers

Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers

Rhabdomyosarcoma is subclassified by the presence or absence of a recurrent chromosome translocation that fuses the <i>FOXO1</i> and <i>PAX3</i> or <i>PAX7</i> genes. The fusion protein (FOXO1-PAX3/7) retains both binding domains and becomes a novel and potent tra...

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Bibliographic Details
Main Authors: Bryan R. Helm, Xiaohui Zhan, Pankita H. Pandya, Mary E. Murray, Karen E. Pollok, Jamie L. Renbarger, Michael J. Ferguson, Zhi Han, Dong Ni, Jie Zhang, Kun Huang
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Genes
Subjects:
rhabdomyosarcoma
gene fusion
gene co-expression analysis
quasi-clique merger
copy number variation
Online Access:https://www.mdpi.com/2073-4425/10/9/665

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https://www.mdpi.com/2073-4425/10/9/665

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