Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease

Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease

Objective and Impact Statement. There is a need to develop platforms delineating inflammatory biology of the distal human lung. We describe a platform technology approach to detect in situ enzyme activity and observe drug inhibition in the distal human lung using a combination of matrix metalloprote...

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Bibliographic Details
Main Authors: Alicia Megia-Fernandez, Adam Marshall, Ahsan R. Akram, Bethany Mills, Sunay V. Chankeshwara, Emma Scholefield, Amy Miele, Bruce C. McGorum, Chesney Michaels, Nathan Knighton, Tom Vercauteren, Francois Lacombe, Veronique Dentan, Annya M. Bruce, Joanne Mair, Robert Hitchcock, Nik Hirani, Chris Haslett, Mark Bradley, Kevin Dhaliwal
Format: Article
Language:English
Published: American Association for the Advancement of Science 2021-01-01
Series:BME Frontiers
Online Access:http://dx.doi.org/10.34133/2021/9834163

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http://dx.doi.org/10.34133/2021/9834163

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