DAF-12 regulates a connected network of genes to ensure robust developmental decisions.

The nuclear receptor DAF-12 has roles in normal development, the decision to pursue dauer development in unfavorable conditions, and the modulation of adult aging. Despite the biologic importance of DAF-12, target genes for this receptor are largely unknown. To identify DAF-12 targets, we performed...

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Bibliographic Details
Main Authors: Daniel Hochbaum, Yue Zhang, Carsten Stuckenholz, Paul Labhart, Vassili Alexiadis, René Martin, Hans-Joachim Knölker, Alfred L Fisher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3140985?pdf=render