An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

A key challenge in antibiotic stewardship is figuring out how to use antibiotics therapeutically without promoting the evolution of antibiotic resistance. Here, we demonstrate proof of concept for an adjunctive therapy that allows intravenous antibiotic treatment without driving the evolution and on...

Full description

Bibliographic Details
Main Authors: Valerie J Morley, Clare L Kinnear, Derek G Sim, Samantha N Olson, Lindsey M Jackson, Elsa Hansen, Grace A Usher, Scott A Showalter, Manjunath P Pai, Robert J Woods, Andrew F Read
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
Enterococcus faecium
antimicrobial resistance
antimicrobial stewardship
evolutionary medicine
daptomycin
Online Access:https://elifesciences.org/articles/58147

Internet

https://elifesciences.org/articles/58147

Similar Items