Sex-specific stress response and HMGB1 release in pulmonary endothelial cells.

Women are known to be associated with a higher susceptibility to pulmonary arterial hypertension (PAH). In contrast, male PAH patients have a worse survival prognosis. In this study, we investigated whether the contribution of sex goes beyond the effects of sex hormones by comparing the ability of i...

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Bibliographic Details
Main Authors: Marina Zemskova, Sergey Kurdyukov, Joel James, Nolan McClain, Ruslan Rafikov, Olga Rafikova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231267