Immunotherapy in small-cell lung cancer: from molecular promises to clinical challenges

Immunotherapy in small-cell lung cancer: from molecular promises to clinical challenges

Abstract Management of small cell lung cancer (SCLC) has not changed over the last decades. In more recent years, alterations of DNA repair machinery and other molecular pathways have been identified in SCLC and preclinical data suggest that dysregulation of these pathways might offer new therapeuti...

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Bibliographic Details
Main Authors: A. Pavan, I. Attili, G. Pasello, V. Guarneri, P. F. Conte, L. Bonanno
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Small cell lung cancer
Immune checkpoint inhibitors
Immunotherapy
Tumor microenvironment
Combination therapy
Enhancer of zeste homolog 2
Online Access:http://link.springer.com/article/10.1186/s40425-019-0690-1

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http://link.springer.com/article/10.1186/s40425-019-0690-1

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