Application of Heparin Affinity Chromatography to Produce a Differential Vaccine without Eliciting Antibodies against the Nonstructural Proteins of the Serotype O Foot-and-Mouth Disease Viruses

Application of Heparin Affinity Chromatography to Produce a Differential Vaccine without Eliciting Antibodies against the Nonstructural Proteins of the Serotype O Foot-and-Mouth Disease Viruses

Although polyethylene glycol (PEG) application is the most widely used method in removing nonstructural proteins (NSPs) for foot-and-mouth disease (FMD) vaccine production, some NSPs remaining in the antigen could elicit antibodies against these proteins after repeated vaccinations in livestock. The...

Full description

Bibliographic Details
Main Authors: Sun Young Park, Jung-Min Lee, Ah-Young Kim, Sang Hyun Park, Jae-Seok Kim, Hyejin Kim, Jung-Won Park, Jong-Hyeon Park, Young-Joon Ko, Choi-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Viruses
Subjects:
foot-and-mouth disease virus
vaccine
nonstructural protein
purification
chromatography
Online Access:https://www.mdpi.com/1999-4915/12/12/1405

Internet

https://www.mdpi.com/1999-4915/12/12/1405

Similar Items