NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice

Abstract Background Major depressive disorder (MDD) is a highly prevalent psychiatric disorder, and inflammation has been considered crucial components of the pathogenesis of depression. NLRP1 inflammasome-driven inflammatory response is believed to participate in many neurological disorders. Howeve...

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Bibliographic Details
Main Authors: Ao-Qi Song, Bo Gao, Jun-Juan Fan, Ya-Jing Zhu, Jun Zhou, Yu-Ling Wang, Li-Zhong Xu, Wen-Ning Wu
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Neuroinflammation
Subjects:
MDD
Online Access:http://link.springer.com/article/10.1186/s12974-020-01848-8