Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease
<p>Abstract</p> <p>The excitotoxin quinolinic acid (QUIN) is synthesized through the kynurenine pathway (KP) by activated monocyte lineage cells. QUIN is likely to play a role in the pathogenesis of several major neuroinflammatory diseases including Alzheimer's disease (AD). T...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-12-01
|
Series: | Journal of Neuroinflammation |
Online Access: | http://www.jneuroinflammation.com/content/6/1/36 |