A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer.

Recently, several classifiers that combine primary tumor data, like gene expression data, and secondary data sources, such as protein-protein interaction networks, have been proposed for predicting outcome in breast cancer. In these approaches, new composite features are typically constructed by agg...

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Bibliographic Details
Main Authors: Christine Staiger, Sidney Cadot, Raul Kooter, Marcus Dittrich, Tobias Müller, Gunnar W Klau, Lodewyk F A Wessels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338754?pdf=render