Chronic Intermittent Hypobaric Hypoxia Ameliorates Ischemia/Reperfusion-Induced Calcium Overload in Heart via Na+/Ca2+ Exchanger in Developing Rats

Chronic Intermittent Hypobaric Hypoxia Ameliorates Ischemia/Reperfusion-Induced Calcium Overload in Heart via Na+/Ca2+ Exchanger in Developing Rats

Background/Aims: Chronic intermittent hypobaric hypoxia (CIHH) protects the heart against ischemia/reperfusion (I/R) injury. This study investigated the calcium homeostasis mechanism and the role of Na+/Ca2+ exchanger (NCX) in the cardiac protective effect of CIHH in developing rats. Methods: Neonat...

Full description

Bibliographic Details
Main Authors: Hui-Jie Ma, Qian Li, Hui-Juan Ma, Yue Guan, Min Shi, Jing Yang, De-Pei Li, Yi Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ischemia/reperfusion
Chronic intermittent hypobaric hypoxia
Cardiac protection
Calcium homeostasis
Na+/Ca2+ exchanger
Cardiomyocyte
Developing rat
Online Access:http://www.karger.com/Article/FullText/363001

Internet

http://www.karger.com/Article/FullText/363001

Similar Items