RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.

We have previously demonstrated that loss of the tumor suppressive activity of ribosomal protein (RP) RPL22 predisposes to development of leukemia in mouse models and aggressive disease in human patients; however, the role of RPL22 in solid tumors, specifically colorectal cancer (CRC), had not been...

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Bibliographic Details
Main Authors: Shuyun Rao, Suraj Peri, Jens Hoffmann, Kathy Q Cai, Bryan Harris, Michele Rhodes, Denise C Connolly, Joseph R Testa, David L Wiest
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222392