Copper-Catalyzed Amination of Vinyl Azides to α-Ketoamides

Copper-Catalyzed Amination of Vinyl Azides to α-Ketoamides

Abstract An efficient approach for the amination of vinyl azides with N,N-dialkylacylamides has been developed. By using this protocol, structurally important α-ketoamides can be easily synthesized. The key to success is not only the introduction of a Cu(I)/oxygen catalytic system but also the utili...

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Bibliographic Details
Main Authors: Yu Wang, Dongling Zhang, Kaining Zhang, Zhenhua Liu, Jing Lin, Wei Cao, Zhongxue Fang
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2019-10-01
Series:SynOpen
Subjects:
amination
α-ketoamide
vinyl azide
copper-catalysis
n,n-dialkylacylamides
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1611922

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1611922

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