PTPRT regulates high-fat diet-induced obesity and insulin resistance.

PTPRT regulates high-fat diet-induced obesity and insulin resistance.

Obesity is a risk factor for many human diseases. However, the underlying molecular causes of obesity are not well understood. Here, we report that protein tyrosine phosphatase receptor T (PTPRT) knockout mice are resistant to high-fat diet-induced obesity. Those mice avoid many deleterious side eff...

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Bibliographic Details
Main Authors: Xiujing Feng, Anthony Scott, Yong Wang, Lan Wang, Yiqing Zhao, Stephanie Doerner, Masanobu Satake, Colleen M Croniger, Zhenghe Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4065109?pdf=render

Internet

http://europepmc.org/articles/PMC4065109?pdf=render

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