The Multifaceted Function of Granzymes in Sepsis: Some Facts and a Lot to Discover

The Multifaceted Function of Granzymes in Sepsis: Some Facts and a Lot to Discover

Sepsis is a serious global health problem. In addition to a high incidence, this syndrome has a high mortality and is responsible for huge health expenditure. The pathophysiology of sepsis is very complex and it is not well-understood yet. However, it is widely accepted that the initial phase of sep...

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Bibliographic Details
Main Authors: Marcela Garzón-Tituaña, Maykel A. Arias, José L. Sierra-Monzón, Elena Morte-Romea, Llipsy Santiago, Ariel Ramirez-Labrada, Luis Martinez-Lostao, José R. Paño-Pardo, Eva M. Galvez, Julián Pardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
sepsis
inflammatory cytokine
granzymes
coagulopathy
endothelial (dys)function
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01054/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01054/full

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