Integrative analyses of single-cell transcriptome and regulome using MAESTRO

Integrative analyses of single-cell transcriptome and regulome using MAESTRO

Abstract We present Model-based AnalysEs of Transcriptome and RegulOme (MAESTRO), a comprehensive open-source computational workflow ( http://github.com/liulab-dfci/MAESTRO ) for the integrative analyses of single-cell RNA-seq (scRNA-seq) and ATAC-seq (scATAC-seq) data from multiple platforms. MAEST...

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Bibliographic Details
Main Authors: Chenfei Wang, Dongqing Sun, Xin Huang, Changxin Wan, Ziyi Li, Ya Han, Qian Qin, Jingyu Fan, Xintao Qiu, Yingtian Xie, Clifford A. Meyer, Myles Brown, Ming Tang, Henry Long, Tao Liu, X. Shirley Liu
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Genome Biology
Subjects:
Single-cell RNA-seq
Single-cell ATAC-seq
Computational workflow
Integrate scRNA-seq and scATAC-seq
Cell-type annotation
Predict transcriptional regulators
Online Access:http://link.springer.com/article/10.1186/s13059-020-02116-x

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http://link.springer.com/article/10.1186/s13059-020-02116-x

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