Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

It is controversially discussed whether immune-deficient mice experience severity in the absence of infection. Because a comprehensive analysis of the well-being of immune-deficient mice under specific pathogen free conditions is missing, we used a multi-parametric test analyzing, corticosterone, we...

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Bibliographic Details
Main Authors: Sarah Jeuthe, Josephine Kemna, Christoph Philipp Kemna, Dario Zocholl, Robert Klopfleisch, Rupert Palme, Clemens Kirschbaum, Christa Thoene-Reineke, Thomas Kammertoens, Yann Herault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526874/?tool=EBI