Regulatory T Cells Maintain Peripheral Tolerance to Islet Allografts Induced by Intrathymic Injection of MHC Class I Allopeptides

Although transplantation remains the treatment of choice for diabetes mellitus, immunological rejection of allografts continues to be a major problem. The search for strategies to prevent graft rejection led us to examine if the fate of developing T cells may be influenced by the presence of allo MH...

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Bibliographic Details
Main Authors: David V. Saborio, Nepal C. Chowdhury, Ming-Xing Jin, Anil Chandraker, Mohamed H. Sayegh, Soji F. Oluwole M.D.
Format: Article
Language:English
Published: SAGE Publishing 1999-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979900800405