Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer.

Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for axon guidance, are now known to play a role in...

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Bibliographic Details
Main Authors: Ying-Hua Yang, Asma Buhamrah, Abraham Schneider, Yi-Ling Lin, Hua Zhou, Amr Bugshan, John R Basile
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4766104?pdf=render