YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling

Abstract Background Pancreatic cancer is a major cause of cancer-related mortality. The identification of effective biomarkers is essential in order to improve management of the disease. Yes-associated protein 1 (YAP1) is a downstream effector of the Hippo pathway, a signal transduction system impli...

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Main Authors: Qimin Zhou, Monika Bauden, Roland Andersson, Dingyuan Hu, György Marko-Varga, Jianfeng Xu, Agata Sasor, Hua Dai, Krzysztof Pawłowski, Katarzyna Said Hilmersson, Xi Chen, Daniel Ansari
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-020-02254-7