Comprehensive analysis of whole genome methylation in mouse blastocysts cultured with four different constituents following in vitro fertilization

Abstract Background With the development of assisted reproductive technology (ART), diseases believed to be caused by ART have begun to be identified as imprinted disease. However, no conclusion has been reached. So we sought to determine whether ART procedures disturb gene methylation and whether i...

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Bibliographic Details
Main Authors: Yu Horibe, Kazuhiko Nakabayashi, Miyuki Arai, Kohji Okamura, Kazunori Hashimoto, Hideo Matsui, Kenichiro Hata
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Middle East Fertility Society Journal
Subjects:
IVF
Online Access:https://doi.org/10.1186/s43043-019-0012-z