Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism.

Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism.

The yeast Saccharomyces cerevisiae undergoes a mitochondrial-dependent programmed cell death in response to different stimuli, such as acetic acid, with features similar to those of mammalian apoptosis. However, the upstream signaling events in this process, including those leading to mitochondrial...

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Main Authors: António Rego, Margarida Costa, Susana Rodrigues Chaves, Nabil Matmati, Helena Pereira, Maria João Sousa, Pedro Moradas-Ferreira, Yusuf A Hannun, Vítor Costa, Manuela Côrte-Real
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511487?pdf=render

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http://europepmc.org/articles/PMC3511487?pdf=render

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