In Vitro Modeling of Reoxygenation Effects on mRNA and Protein Levels in Hypoxic Tumor Cells upon Entry into the Bloodstream

Background: Solid epithelial tumors like breast cancer are the most frequent malignancy in women. Circulating tumor cells (CTCs) are frequently released from hypoxic areas into the blood, where CTCs face elevated oxygen concentrations. This reoxygenation might challenge the use of CTCs for liquid bi...

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Bibliographic Details
Main Authors: Kai Bartkowiak, Claudia Koch, Sebastian Gärtner, Antje Andreas, Tobias M Gorges, Klaus Pantel
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/5/1316