Preclinical and Clinical Development of a YFV 17 D-Based Chimeric Vaccine against West Nile Virus

Substantial success has been achieved in the development and implementation of West Nile (WN) vaccines for horses; however, no human WN vaccines are approved. This review focuses on the construction, pre-clinical and clinical characterization of ChimeriVax-WN02 for humans, a live chimeric vaccine co...

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Bibliographic Details
Main Authors: Gustavo H. Dayan, Konstantin Pugachev, Joan Bevilacqua, Jean Lang, Thomas P. Monath
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/5/12/3048