A comparison of methods for clustering 16S rRNA sequences into OTUs.

Recent studies of 16S rRNA sequences through next-generation sequencing have revolutionized our understanding of the microbial community composition and structure. One common approach in using these data to explore the genetic diversity in a microbial community is to cluster the 16S rRNA sequences i...

Full description

Bibliographic Details
Main Authors: Wei Chen, Clarence K Zhang, Yongmei Cheng, Shaowu Zhang, Hongyu Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3742672?pdf=render