Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling

Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling

Chuhai Xie, Boyi Wu, Binwei Chen, Qunwei Shi, Jianhong Guo, Ziwen Fan, Yan Huang Department of Orthopedics, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China Abstract: Histone deacetylase inhibitors have been reported to induce...

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Bibliographic Details
Main Authors: Xie C, Wu B, Chen B, Shi Q, Guo J, Fan Z, Huang Y
Format: Article
Language:English
Published: Dove Medical Press 2016-07-01
Series:OncoTargets and Therapy
Subjects:
Osteosarcoma
Histone deacetylase inhibitor
Sodium butyrate
MDM2-p53 feedback loop
Online Access:https://www.dovepress.com/histone-deacetylase-inhibitor-sodium-butyrate-suppresses-proliferation-peer-reviewed-article-OTT

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https://www.dovepress.com/histone-deacetylase-inhibitor-sodium-butyrate-suppresses-proliferation-peer-reviewed-article-OTT

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