Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs

Systems Biology Analysis Reveals Eight SLC22 Transporter Subgroups, Including OATs, OCTs, and OCTNs

The SLC22 family of OATs, OCTs, and OCTNs is emerging as a central hub of endogenous physiology. Despite often being referred to as “drug” transporters, they facilitate the movement of metabolites and key signaling molecules. An in-depth reanalysis supports a reassignment of thes...

Full description

Bibliographic Details
Main Authors: Darcy C. Engelhart, Jeffry C. Granados, Da Shi, Milton H. Saier Jr., Michael E. Baker, Ruben Abagyan, Sanjay K. Nigam
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
transporters
endogenous metabolism
functional subgroups
slc22
remote sensing and signaling
drug transporters
gut microbiome
chronic kidney disease
Online Access:https://www.mdpi.com/1422-0067/21/5/1791

Internet

https://www.mdpi.com/1422-0067/21/5/1791

Similar Items