Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease

Increasing evidence suggests that gasdermin D (GSDMD) mediated pyroptosis signaling pathways play a vital role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Jiangzhi Ligan Decoction (JZLGD) has been verified to prevent NAFLD, but its specific mechanism has not been determined. In...

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Bibliographic Details
Main Authors: Kangkang Yin, Xiao Zhou, Wei Jiang, Linlin Wang, Ziwei Dai, Biao Tang
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2021/9963534