Factors that influence quality and yield of circulating-free DNA: A systematic review of the methodology literature

Background: Circulating-free DNA (cfDNA) is under investigation as a liquid biopsy of cancer for early detection, monitoring disease progression and therapeutic response. This systematic review of the primary cfDNA literature aims to identify and evaluate factors that influence recovery of cfDNA, an...

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Bibliographic Details
Main Authors: R.M. Trigg, L.J. Martinson, S. Parpart-Li, J.A. Shaw
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017339129