Concomitant treatment with imipenem causes a rapid and extensive decrease in the plasma concentrations of valproic acid
Background. Valproic acid (VPA) is a wide-spectrum antiepileptic drug used both in children and in adults. We describe a clinically important interaction between VPA and imipenem, a carbapenem antimicrobial.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Exeley Inc.
2016-06-01
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| Series: | Journal of Epileptology |
| Subjects: | |
| Online Access: | http://www.degruyter.com/view/j/joepi.2016.24.issue-1/joepi-2016-0006/joepi-2016-0006.xml?format=INT |