Genetic and epigenetic characteristics in ovarian tissues from polycystic ovary syndrome patients with irregular menstruation resemble those of ovarian cancer

Genetic and epigenetic characteristics in ovarian tissues from polycystic ovary syndrome patients with irregular menstruation resemble those of ovarian cancer

Abstract Background Irregular menstruation is clinically associated with an increased risk for ovarian cancer and disease-related mortality. This relationship remains poorly understood, and a mechanism explaining it has yet to be described. Methods Ovarian tissues from women with polycystic ovary sy...

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Bibliographic Details
Main Authors: Jiao Jiao, Matthew Sagnelli, Bei Shi, Yuanyuan Fang, Ziqi Shen, Tianyu Tang, Bingying Dong, Da Li, Xiuxia Wang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Endocrine Disorders
Subjects:
PCOS
Irregular menstruation
Ovarian Cancer
BRCA1
MLH1
Online Access:http://link.springer.com/article/10.1186/s12902-019-0356-5

Internet

http://link.springer.com/article/10.1186/s12902-019-0356-5

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