Single nucleolus precursor body formation in the pronucleus of mouse zygotes and SCNT embryos.
Mammalian oocytes and zygotes have nucleoli that are transcriptionally inactive and structurally distinct from nucleoli in somatic cells. These nucleoli have been termed nucleolus precursor bodies (NPBs). Recent research has shown that NPBs are important for embryonic development, but they are only...
Main Authors: | Hirohisa Kyogoku, Teruhiko Wakayama, Tomoya S Kitajima, Takashi Miyano |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6101414?pdf=render |
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