Single nucleolus precursor body formation in the pronucleus of mouse zygotes and SCNT embryos.

Mammalian oocytes and zygotes have nucleoli that are transcriptionally inactive and structurally distinct from nucleoli in somatic cells. These nucleoli have been termed nucleolus precursor bodies (NPBs). Recent research has shown that NPBs are important for embryonic development, but they are only...

Full description

Bibliographic Details
Main Authors: Hirohisa Kyogoku, Teruhiko Wakayama, Tomoya S Kitajima, Takashi Miyano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6101414?pdf=render