MicroRNA-223 inhibits neutrophil extracellular traps formation through regulating calcium influx and small extracellular vesicles transmission

Abstract Modulation of miRNAs and neutrophil extracellular traps (NETs) formation are both implicated in inflammatory disorders. Adult-onset Still’s disease (AOSD) is a systemic autoinflammatory disease with neutrophilic leukocytosis and unknown etiology. Although the NETs formation is elevated in A...

Full description

Bibliographic Details
Main Authors: Tsai-Ling Liao, Yi-Ming Chen, Kuo-Tung Tang, Po-Ku Chen, Hung-Jen Liu, Der-Yuan Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95028-0