Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice

Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice

Background: Pyroptosis is the term for caspase-1-dependent cell death associated with pro-inflammatory cytokines. The role of alveolar macrophage (AM) pyroptosis in the pathogenesis of the acute lung injury and acute respiratory distress syndrome (ALI/ARDS) remains unclear. Methods: C57BL/6 wild-typ...

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Bibliographic Details
Main Authors: Dong-Dong Wu, Pin-Hua Pan, Ben Liu, Xiao-Li Su, Le-Meng Zhang, Hong-Yi Tan, Zu Cao, Zuo-Ren Zhou, Hai-Tao Li, Hao-Si Li, Li Huang, Yuan-Yuan Li
Format: Article
Language:English
Published: Wolters Kluwer 2015-01-01
Series:Chinese Medical Journal
Subjects:
Acute Lung Injury/Acute Respiratory Distress Syndrome; Alveolar Macrophage; Caspase-1; Pyroptosis
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=19;spage=2638;epage=2645;aulast=Wu

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http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=19;spage=2638;epage=2645;aulast=Wu

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