A Novel Pathway for the Biosynthesis of Heme in Archaea: Genome-Based Bioinformatic Predictions and Experimental Evidence

Heme is an essential prosthetic group for many proteins involved in fundamental biological processes in all three domains of life. In Eukaryota and Bacteria heme is formed via a conserved and well-studied biosynthetic pathway. Surprisingly, in Archaea heme biosynthesis proceeds via an alternative ro...

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Bibliographic Details
Main Authors: Sonja Storbeck, Sarah Rolfes, Evelyne Raux-Deery, Martin J. Warren, Dieter Jahn, Gunhild Layer
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Archaea
Online Access:http://dx.doi.org/10.1155/2010/175050