Asymmetric Total Syntheses of Both Enantiomers of Plymuthipyranone B and Its Unnatural Analogues: Evaluation of <i>anti</i>-MRSA Activity and Its Chiral Discrimination

Asymmetric Total Syntheses of Both Enantiomers of Plymuthipyranone B and Its Unnatural Analogues: Evaluation of <i>anti</i>-MRSA Activity and Its Chiral Discrimination

Chiral total syntheses of both enantiomers of the <i>anti</i>-MRSA active plymuthipyranone B and all of the both enantiomers of three unnatural and synthetic analogues were performed. These two pairs of four chiral compounds are composed of the same 3-acyl-5,6-dihydro-2<i>H</i&g...

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Bibliographic Details
Main Authors: Mizuki Moriyama, Xiaoxi Liu, Yuki Enoki, Kazuaki Matsumoto, Yoo Tanabe
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
<i>anti</i>-MRSA activity
asymmetric total syntheses
enantiomers
chiral discrimination
plymuthipyranone B
Online Access:https://www.mdpi.com/1424-8247/14/9/938

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https://www.mdpi.com/1424-8247/14/9/938

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