U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing

Splicing factor 3b subunit 1 (SF3B1) is an essential protein in spliceosomes and mutated frequently in many cancers. While roles of SF3B1 in single intron splicing and roles of its cancer-linked mutant in aberrant splicing have been identified to some extent, regulatory functions of wild-type SF3B1...

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Bibliographic Details
Main Authors: Namjeong Choi, Yongchao Liu, Jagyeong Oh, Jiyeon Ha, Xuexiu Zheng, Haihong Shen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
SMN
Online Access:https://www.mdpi.com/2073-4409/9/12/2647