Carcinoma-Associated Fibroblasts Promote Growth of Sox2-Expressing Breast Cancer Cells

CAFs (Carcinoma-associated fibroblasts) play an important role in cancer progression. For instance, they promote resistance to anti-estrogens, such as fulvestrant. Here, we show that, in ERα-positive breast cancer cell lines, the cocktail of factors secreted by CAFs (CAF-CM) induce the expression of...

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Bibliographic Details
Main Authors: Angela Dittmer, Jürgen Dittmer
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
AKT
Online Access:https://www.mdpi.com/2072-6694/12/11/3435