Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells
Introduction: The nuclear factor-κB (NF-κB) is an important regulator of the inflammatory response. Angiotensin II (Ang II) activates the NF-κB pathway linked to renal inflammation. Although both AT 1 and AT 2 receptors are involved in Ang II-mediated NF-κB activation, the biological processes media...
Main Authors: | Matilde Alique, Elsa Sánchez-López, Sandra Rayego-Mateos, Jesús Egido, Alberto Ortiz, Marta Ruiz-Ortega |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2015-03-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320314551564 |
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