Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells

Introduction: The nuclear factor-κB (NF-κB) is an important regulator of the inflammatory response. Angiotensin II (Ang II) activates the NF-κB pathway linked to renal inflammation. Although both AT 1 and AT 2 receptors are involved in Ang II-mediated NF-κB activation, the biological processes media...

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Bibliographic Details
Main Authors: Matilde Alique, Elsa Sánchez-López, Sandra Rayego-Mateos, Jesús Egido, Alberto Ortiz, Marta Ruiz-Ortega
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320314551564