GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology

GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology

GABAergic mechanisms are critically involved in the control of fear and anxiety, but their role in the development of stress-induced psychopathologies, including post-traumatic stress disorder (PTSD) and mood disorders is not sufficiently understood. We studied these functions in two established mou...

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Bibliographic Details
Main Authors: Iris eMüller, Kunihiko eObata, Gal eRichter-Levin, Oliver eStork
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Glutamate Decarboxylase
Social Isolation
posttraumatic stress disorder
stress resilience
juvenile trauma
mutant mouse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00265/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00265/full

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