ZNF300 knockdown inhibits forced megakaryocytic differentiation by phorbol and erythrocytic differentiation by arabinofuranosyl cytidine in K562 cells.

Previously, we reported that ZNF300 might play a role in leukemogenesis. In this study, we further investigated the function of ZNF300 in K562 cells undergoing differentiation. We found that ZNF300 upregulation in K562 cells coincided with megakaryocytic differentiation induced by phorbol-12-myrista...

Full description

Bibliographic Details
Main Authors: Jinyang Cai, Rui Gong, Fengjuan Yan, Chunjie Yu, Lu Liu, Wei Wang, Yi Lin, Mingxiong Guo, Wenxin Li, Zan Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259388?pdf=render