A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency

SynGAP is a postsynaptic density (PSD) protein that binds to PDZ domains of the scaffold protein PSD-95. We previously reported that heterozygous deletion of Syngap1 in mice is correlated with increased steady-state levels of other key PSD proteins that bind PSD-95, although the level of PSD-95 rema...

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Bibliographic Details
Main Authors: Tara L Mastro, Anthony Preza, Shinjini Basu, Sumantra Chattarji, Sally M Till, Peter C Kind, Mary B Kennedy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/52656