An interplay of microglia and matrix metalloproteinase MMP9 under hypoxic stress regulates the opticin expression in retina

An interplay of microglia and matrix metalloproteinase MMP9 under hypoxic stress regulates the opticin expression in retina

Abstract Inflammation plays a key role in the pathogenesis of retinal vascular diseases. We have shown earlier an increase in the activity of matrix metalloproteinases in the vitreous and tears of preterm born babies with retinopathy of prematurity (ROP) compared to those with no-ROP leading to a sh...

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Main Authors: Satish Patnaik, Meenakshi Rai, Subhadra Jalali, Komal Agarwal, Akshay Badakere, Lavanya Puppala, Sushma Vishwakarma, Divya Balakrishnan, Padmaja K. Rani, Ramesh Kekunnaya, Preeti Patil Chhablani, Subhabrata Chakrabarti, Inderjeet Kaur
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86302-2

Internet

https://doi.org/10.1038/s41598-021-86302-2

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