Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment

Synaptotagmin (syt) 7 is one of three syt isoforms found in all metazoans; it is ubiquitously expressed, yet its function in neurons remains obscure. Here, we resolved Ca2+-dependent and Ca2+-independent synaptic vesicle (SV) replenishment pathways, and found that syt 7 plays a selective and critica...

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Bibliographic Details
Main Authors: Huisheng Liu, Hua Bai, Enfu Hui, Lu Yang, Chantell S Evans, Zhao Wang, Sung E Kwon, Edwin R Chapman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01524