Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers

Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers

Abstract Recent advances in our understanding of the dynamics of cellular cross-talk have highlighted the significance of host-versus-tumor effect that can be harnessed with immune therapies. Tumors exploit immune checkpoints to evade adaptive immune responses. Cancer immunotherapy has witnessed a r...

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Bibliographic Details
Main Authors: Muhammad Umair Mushtaq, Athanasios Papadas, Adam Pagenkopf, Evan Flietner, Zachary Morrow, Sibgha Gull Chaudhary, Fotis Asimakopoulos
Format: Article
Language:English
Published: BMJ Publishing Group 2018-07-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Adaptive immune response
Immune checkpoint inhibitors
Immunotherapy
Tumor microenvironment
Matrix remodeling
Immune biomarkers
Online Access:http://link.springer.com/article/10.1186/s40425-018-0376-0

Internet

http://link.springer.com/article/10.1186/s40425-018-0376-0

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