Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease

Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease

Theoretical inferences, based on biophysical, biochemical, and biosemiotic considerations, are related here to the pathogenesis of cardiovascular disease, diabetes, and other degenerative conditions. We suggest that the “daytime” job of endothelial nitric oxide synthase (...

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Bibliographic Details
Main Authors: Stephanie Seneff, Ann Lauritzen, Robert Davidson, Laurie Lentz-Marino
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Entropy
Subjects:
endothelial nitric oxide synthase
diabetes
cardiovascular disease
cholesterol sulfate
lysosomes
autophagy
heparan sulfate
hydrogen sulfide
nitric oxide
glycosaminoglycans
Online Access:http://www.mdpi.com/1099-4300/14/12/2492

Internet

http://www.mdpi.com/1099-4300/14/12/2492

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