Allelic variants of <it>IL1R1 </it>gene associate with severe hand osteoarthritis

<p>Abstract</p> <p>Background</p> <p>In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to s...

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Main Authors: Harilainen Arsi, Saarela Janna, Kouhia Sanna T, Näkki Annu, Tallroth Kaj, Videman Tapio, Battié Michele C, Kaprio Jaakko, Peltonen Leena, Kujala Urho M
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/11/50